专题

基于虚拟现实技术治疗抑郁障碍的专家共识

  • 李春波 ,
  • 张彩迪 ,
  • 杨璧西 ,
  • 杨宇晴 ,
  • 廖晨曦 ,
  • 师彬彬 ,
  • 罗金晶 ,
  • 朱智佩 ,
  • 吴佳佳 ,
  • 华续赟 ,
  • 郑谋雄 ,
  • 单春雷 ,
  • 徐建光
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  • 1上海交通大学医学院附属精神卫生中心,上海 200030;
    2上海交通大学心理学院,上海 200030;
    3上海市重性精神病重点实验室,上海 200030;
    4中医智能康复教育部工程研究中心,上海 201203;
    5上海中医药大学附属岳阳中西医结合医院康复医学中心,上海 200437;
    6上海中医药大学康复医学院,上海 201203
李春波,医学博士,主任医师。研究方向:主要从事认知老化可塑性、精神病理学和循证医学研究。

网络出版日期: 2024-11-22

基金资助

国家科技部重点研发计划项目(2018YFC2001600, 2018YFC2001605); 上海市精神心理临床医学研究中心(19MC191 1100); 上海市精神卫生中心“启航计划”人才项目(2021-QH-01)

Expert Consensus on the Use of Virtual Reality Technology for the Treatment of Depressive Disorders

  • LI Chunbo ,
  • ZHANG Caidi ,
  • YANG Bixi ,
  • YANG Yuqing ,
  • LIAO Chenxi ,
  • SHI Binbin ,
  • LUO Jinjing ,
  • ZHU Zhipei ,
  • WU Jiajia ,
  • HUA Xuyun ,
  • ZHENG Mouxiong ,
  • SHAN Chunlei ,
  • XU Jianguang
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  • 1Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China;
    2School of Psychology, Shanghai Jiao Tong University, Shanghai 200030, China;
    3Shanghai Key Laboratory of Psychotic Disorders, Shanghai 200030, China;
    4Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation, Ministry of Education, Shanghai 201203, China;
    5Center of Rehabilitation Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China;
    6School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

Online published: 2024-11-22

摘要

虚拟现实技术(virtual reality,VR)具有沉浸性和交互性的特点,兼有场景安全、可控、可重复的特点,其在抑郁障碍心理治疗领域应用前景广阔。为规范VR心理干预在抑郁障碍患者中的临床应用,本专家共识采用改良德尔菲法,联合19位精神医学及相关专业领域的专家,系统检索并回顾了临床证据而形成。共识明确了VR治疗抑郁障碍的开发原则、内容要求和应用范围,基于以往临床证据提供了临床应用的推荐意见,并探讨了不良反应和治疗流程。本共识旨在优化VR心理干预在抑郁障碍患者中的临床应用,同时促进其规范化发展,以期改善当前精神障碍心理治疗资源匮乏的现状。

本文引用格式

李春波 , 张彩迪 , 杨璧西 , 杨宇晴 , 廖晨曦 , 师彬彬 , 罗金晶 , 朱智佩 , 吴佳佳 , 华续赟 , 郑谋雄 , 单春雷 , 徐建光 . 基于虚拟现实技术治疗抑郁障碍的专家共识[J]. 心理学通讯, 2024 , 7(2) : 94 -106 . DOI: 10.12100/j.issn.2096-5494.224013

Abstract

Virtual Reality (VR) technology, characterized by its immersive and interactive nature, as well as the safety, controllability, and repeatability of its scenarios, holds broad prospects in the field of psychotherapy for depressive disorders. To standardize the clinical application of VR psychological interventions in people with depression, this expert consensus employed a modified Delphi method, integrated the opinions of 19 experts from psychiatry and related specialties, and systematically reviewed clinical evidence. The consensus clarified the development principles, content requirements, and application scope of VR psychological intervention for depressive disorders. It provided recommendations for clinical application based on related clinical evidence and discussed adverse reactions and treatment processes. The aim of this consensus is to optimize the clinical application of VR psychological intervention in people with depression, promote its standardized development, and thereby improving the current situation of scarce psychological treatment resources for mental disorders.

参考文献

[1] 董莹盈, 崔丹丹, 谢渭根, 任雪英, 钱小芳. (2022). 优化后VR眼镜在治疗抑郁症患者消极情绪中的作用. 中国医药科学,12(24), 142-144.
[2] 孙枞昊, 费锦锋, 金欣, 戴红, 陈静, 吕亮. (2021). 艾司西酞普兰联合虚拟现实认知行为疗法治疗抑郁症的临床观察. 中国现代医生,59(29), 108-112.
[3] 杨璧西. (2022). 基于虚拟现实针对抑郁相关负性自动想法识别训练系统的开发及可行性研究 (博士学位论文). 上海交通大学.
[4] 杨璧西,李春波. (2020). 移动应用程序在抑郁症心理治疗中的研究进展.中华精神科杂志,53(4), 360-363.
[5] 杨宇晴,廖晨曦,杨璧西,赵冰蕾,张彩迪,李春波.(2024). 中文版虚拟治疗关系量表在具有抑郁症状人群中的信效度检验. 同济大学学报(医学版),45(3), 359-365.
[6] 张婷婷. (2022). 基于脑电的抑郁症识别及虚拟现实康复训练研究(硕士论文). 常州大学.
[7] Abeele V. V., Schraepen B., Huygelier H., Gillebert C., Gerling K., & Van Ee R. (2021). Immersive Virtual Reality for Older Adults: Empirically Grounded Design Guidelines.ACM Trans Access Comput, 14(3), 1-30. doi: 10.1145/3470743
[8] Baghaei N., Chitale V., Hlasnik A., Stemmet L., Liang H. N., & Porter R. (2021). Virtual reality for supporting the treatment of depression and anxiety: Scoping review.JMIR Ment Heal, 8(9), e29681. doi: 10.2196/29681
[9] Behr K. M., Nosper A., Klimmt C., & Hartmann T. (2005). Some practical considerations of ethical issues in VR research.Presence, 14(6), 668-676. doi: 10.1162/105474605775196535
[10] Birckhead B., Khalil C., Liu X., Conoyitz S., Rizzo A., Danovitch I., … Spiegel B. (2019). Recommendations for methodology of virtual reality clinical trials in health care by an international working group: Iterative study.JMIR Ment Heal, 6(1), e11973. doi: 10.2196/11973
[11] Blank R., Barnett A. L., Cairney J., Green D., Kirby A., Polatajko H., … Vincon S. (2019). International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder.Dev Med Child Neurol, 61(3), 242-285. doi: 10.1111/dmcn.14132
[12] Bolinski F., Etzelmuller A., De Witte N. A., van Beurden C., Debard G., Bonroy B., … Kleiboer A. (2021). Physiological and self-reported arousal in virtual reality versus face-to-face emotional activation and cognitive restructuring in university students: A crossover experimental study using wearable monitoring.Behav Res Ther, 142, 103877. doi: 10.1016/j.brat.2021.103877
[13] Budimlic S. P., Rajnar R., Kambic L., Janša J., Koritnik R., Trpkov K., … Trošt M. (2016). The effects of Nintendo Wii balance board training on walking, quality of life and depression in Parkinson’s disease patients-Pilot study.J Parkinsons Dis, 6, 199-200. doi: 10.3233/JPD-169900
[14] Carlbring P., Hadjistavropoulos H., Kleiboer A., & Andersson G. (2023). A new era in Internet interventions: The advent of Chat-GPT and AI-assisted therapist guidance.Internet Interv, 32, 100621. doi: 10.1016/j.invent.2023.100621
[15] Chardonnet J. R., Mirzaei M. A., & Merienne F. (2021). Influence of navigation parameters on cybersickness in virtual reality.Virtual Real, 25(3), 565-574. doi: 10.1007/s10055-020-00474-2
[16] Cieślik B., Juszko K., Kiper P., & Szczepanska-Gieracha J. (2023). Immersive virtual reality as support for the mental health of elderly women: a randomized controlled trial.Virtual Real, 27(3), 2227-2235. doi: 10.1007/s10055-023-00797-w
[17] Colombo D., Suso-Ribera C., Ortigosa-Beltran I., Fernandez-alvarez J., Garcia-Palacios A., & Botella C. (2022). Behavioral activation through virtual reality for depression: A single case experimental design with multiple baselines.J Clin Med, 11(5), 1262. doi: 10.3390/jcm11051262
[18] Cooney P., O’Reilly G., Jackman C., & Coyle D. (2016). The feel good island: Evaluating the effectiveness of a technology based CBT intervention for adults with an intellectual disability and anxiety or depression.J Cyber Ther Rehabil, 9(1), 27.
[19] Craig T. K., Rus-Calafell M., Ward T., Leff J. P., Huckvale M., Howarth E., … Garety P. A. (2018). AVATAR therapy for auditory verbal hallucinations in people with psychosis: A single-blind, randomised controlled trial.Lancet Psychiatry, 5(1), 31-40. doi: 10.1016/S2215-0366(17)30427-3
[20] Cuijpers P., Kleiboer A., Karyotaki E., & Riper H. (2017). Internet and mobile interventions for depression: Opportunities and challenges.Depress Anxiety, 34(7), 596-602. doi: 10.1002/da.22641
[21] Ding X., Lee Y. W., & Kim C. Y. (2022). A study on the effect of VR content on sub-syndromatic depression of Chinese students in Korea: Based on attention restoration theory (ART).J KOREA Multimed Soc, 25(1), 123-134.
[22] Donker T., Griffiths K. M., Cuijpers P., & Christensen H. (2009). Psychoeducation for depression, anxiety and psychological distress: A meta-analysis.BMC Med, 7, 79. doi: 10.1186/1741-7015-7-79
[23] Ezawa I., Hollon S., & Robinson N. (2023). Examining predictors of depression and anxiety symptom change in cognitive behavioral immersion: Observational study.JMIR Ment Heal, 10, e42377. doi: 10.2023/1/e42377
[24] Fadeev K. A., Smirnov A. S., Zhigalova O. P., Bazhina P. S., Tumialis A. V., & Golokhvast K. S. (2020). Too real to be virtual: Autonomic and EEG responses to extreme stress scenarios in virtual reality.Behav Neurol, 2020, 5758038. doi: 10.1155/2020/5758038
[25] Falconer C. J., Rovira A., King J. A., Gilbert P., Antley A., Fearon P., … Brewin C. R. (2016). Embodying self-compassion within virtual reality and its effects on patients with depression.BJPsych Open, 2(1), 74-80. doi: 10.1192/bjpo.bp.115.002147
[26] Fernandez-Alvarez J., Colombo D., Suso-Ribera C., Chirico A., Serino S., Di Lernia D., … Botella C. (2021). Using virtual reality to target positive autobiographical memory in individuals with moderate-to-moderately severe depressive symptoms: A single case experimental design.Internet Interv, 25, 100407. doi: 10.1016/j.invent.2021.100407
[27] Floriou-Servou A., von Ziegler L., Waag R., Schläppi C., Germain P. L., & Bohacek J. (2021). The acute stress response in the multiomic era.Biol Psychiatry, 89(12), 1116-1126. doi: 10.1016/j.biopsych.2020.12.031
[28] Fluckiger C., Del Re A. C., Wampold B. E., & Horvath A. O. (2018). The alliance in adult psychotherapy: A meta-analytic synthesis.Psychotherapy, 55(4), 316-340. doi: 10.1037/pst0000172
[29] Freeman D., Lambe S., Kabir T., Petit A., Rosebrock L., Yu L. M., … Grp G. T. (2022). Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): A multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses.Lancet Psychiatry, 9(5), 375-388. doi: 10.1016/S2215-0366(22)00060-8
[30] Freher N. K., Bexkens A., van Bennekom M., Veling W., & Bockting C. L. (2022). Virtual reality for psycho-education on self-stigma in depression: Design of a randomised controlled trial.Psychiatry Res Commun, 2(4), 10086. doi: 10.1016/j.psycom.2022.100086
[31] Geraets C. N., van der Stouwe, E. C. D., Pot-Kolder R., & Veling W. (2021). Advances in immersive virtual reality interventions for mental disorders: A new reality?Curr Opin Psychol, 41, 40-45. doi: 10.1016/j.copsyc.2021.02.004
[32] Heim E., Rotger A., Lorenz N., & Maercker A. (2018). Working alliance with an avatar: How far can we go with internet interventions?Internet Interv, 11, 41-46. doi: 10.1016/j.invent.2018.01.005
[33] Horvath, A. O., & Greenberg, L. S. (1989). Development and validation of the working alliance inventory.J Couns Psychol, 36(2), 223-233. doi: 10.1037/0022-0167.36.2.223
[34] Hsieh C. H., Chen C. M., Yang J. Y., Lin Y. J., Liao M. L., & Chueh K. H. (2022). The effects of immersive garden experience on the health care to elderly residents with mild-to-moderate cognitive impairment living in nursing homes after the COVID-19 pandemic.Landsc Ecol Eng, 18(1), 45-56. doi: 10.1007/s11355-021-00480-9
[35] Huang Y., Wang Y., & Wang H. (2019). Prevalence of mental disorders in China: A cross-sectional epidemiological study.Lancet Psychiatry, 6(4), E11-E11. doi: 10.1016/S2215-0366(19)30074-4
[36] Kaup K. K., Vasser M., Tulver K., Munk M., Pikamae J., & Aru J. (2023). Psychedelic replications in virtual reality and their potential as a therapeutic instrument: An open-label feasibility study.Front Psychiatry, 14, 1088896. doi: 10.3389/fpsyt.2023.1198103
[37] Kavradim T. S., Yangöz Ş. T., & Özer Z. (2023). Effectiveness of virtual reality interventions on physiological and psychological outcomes of adults with cardiovascular disease: A systematic review and meta-analysis.J Nurs Scholarsh, 55(5), 949-966. doi: 10.1111/jnu.12885
[38] Kennedy R. S., Lane N. E., Berbaum K. S., & Lilienthal M. G. (1993). Simulator sickness questionnaire: An enhanced method for quantifying simulator sickness.Int J Aviat Psychol, 3(3), 203-220. doi: 10.1207/s15327108ijap0303_3
[39] Kilic, S., & Dereli Yilmaz, S. (2023). Virtual reality headset simulating a nature environment to improve health outcomes in pregnant women: A randomized-controlled trial.Clin Nurs Res, 32(8), 1104-1114. doi: 10.1177/10547738231184923
[40] Kim M., Choi S. W., Moon S., Park H. I., Hwang H., Kim M. K., & Seok J. H. (2020). Treatment effect of psychoeducation and training program using virtual reality technique in the patients with depressive symptoms.J KOREAN Neuropsychiatr Assoc, 59(1), 51-60. doi: 10.4306/jknpa.2020.59.1.51
[41] Kim Y., Hong S., & Choi M. (2022). Effects of serious games on depression in older adults: Systematic review and meta-analysis of randomized controlled trials.J Med Internet Res, 24(9), e37753. doi: 10.2196/37753
[42] Kocur M., Dechant M., Wolff C., Nothdurfter C., Wetter T. C., Rupprecht R., & Shiban Y. (2021). Computer-assisted avatar-based treatment for dysfunctional beliefs in depressive inpatients: A pilot study.Front Psychiatry, 12, 608997. doi: 10.3389/fpsyt.2021.608997
[43] Lewis, C. H., & Griffin, M. J. (1997). Human factors consideration in clinical applications of virtual reality.Stud Health Technol Inform, 44, 35-56.
[44] Lindner P., Hamilton W., Miloff A., & Carlbring P. (2019). How to treat depression with low-intensity virtual reality interventions: Perspectives on translating cognitive behavioral techniques into the virtual reality modality and how to make anti-depressive use of virtual reality-unique experiences.Front Psychiatry, 10, 792. doi: 10.3389/fpsyt.2019.00792
[45] Lu J., Xu X., Huang Y., Li T., Ma C., Xu G., … Zhang N. (2021). Prevalence of depressive disorders and treatment in China: A cross-sectional epidemiological study.Lancet Psychiatry, 8(11), 981-990. doi: 10.1016/S2215-0366(21)00251-0
[46] Mazgelyte E., Zagorskaja J., Dereskeviciute E., Petrenas T., Kaminskas A., Songailiene J., … Karciauskaite D. (2022). Dynamics of physiological, biochemical and psychological markers during single session of virtual reality-based respiratory biofeedback relaxation.Behav Sci (Basel), 12(12), 482. doi: 10.3390/bs12120482
[47] McHugh R. K., Whitton S. W., Peckham A. D., Welge J. A., & Otto M. W. (2013). Patient preference for psychological vs pharmacologic treatment of psychiatric disorders: A meta-analytic review.J Clin Psychiatry, 74(6), 595-602. doi: 10.4088/JCP.12r07757
[48] Miloff A., Carlbring P., Hamilton W., Andersson G., Reuterskiold L., & Lindner P. (2020). Measuring alliance toward embodied virtual therapists in the era of automated treatments with the virtual therapist alliance scale (VTAS): Development and psychometric evaluation.J Med INTERNET Res, 22(3), e16660. doi: 10.2196/16660
[49] Mummah S. A., Robinson T. N., King A. C., Gardner C. D., & Sutton S. (2016). IDEAS (Integrate, Design, Assess, and Share): A framework and toolkit of strategies for the development of more effective digital interventions to change health behavior.J Med Internet Res, 18(12), e317. doi: 10.2196/jmir.5927
[50] Niederberger, M., & Spranger, J. (2020). Delphi technique in health sciences: A map.Front Public Heal, 8, 457 doi: 10.3389/fpubh.2020. 00457
[51] Otkhmezuri, B. Z. (2020). The Design of Virtual Reality Applications for Psychological Interventions. Doctor of Philosophy (PhD) thesis, University of Kent (United Kingdom).
[52] Pan X., Zhang Y., Ren D., Lu L., Wang Y., Li G., .. Bai Y. (2022). Virtual reality in treatment for psychological problems in first-line health care professionals fighting COVID-19 pandemic: A case series.J Nerv Ment Dis, 210(10), 754-759. doi: 10.1097/NMD.0000000000001531
[53] Paul M., Bullock K., & Bailenson J. (2020). Virtual reality behavioral activation as an intervention for major depressive disorder: Case report.JMIR Ment Heal, 7(11), e24331. doi: 10.2196/24331
[54] Paul M., Bullock K., & Bailenson J. (2022). Virtual reality behavioral activation for adults with major depressive disorder: Feasibility randomized controlled trial.JMIR Ment Heal, 9(5), e35526. doi: 10.2196/35526
[55] Plencler I., Kruk D., Daren A., Stankiewicz P., Nowak A., Radon S., … Siwek M. (2022). The effects of mindfulness-based training in virtual reality on psychotic symptoms, mood and cognitive functioning: A pilot study.Psychiatr Pol, 58(2), 289-302. doi: 10.12740/PP/OnlineFirst/154033
[56] Pot-Kolder R. M., Geraets C. N., Veling W., van Beilen M., Staring A. B., Gijsman H. J., .. van der Gaag, M. (2018). Virtual-reality-based cognitive behavioural therapy versus waiting list control for paranoid ideation and social avoidance in patients with psychotic disorders: A single-blind randomised controlled trial.Lancet Psychiatry, 5(3), 217-226. doi: 10.1016/S2215-0366(18)30053-1
[57] Proudfoot, J. G. (2004). Computer-based treatment for anxiety and depression: Is it feasible? Is it effective?Neurosci Biobehav Rev, 28(3), 353-363. doi: 10.1016/j.neubiorev.2004.03.008
[58] Prudenzi A., Rooney B., Presti G., Lombardo M., Lombardo D., Messina C., & McHugh L. (2019). Testing the effectiveness of virtual reality as a defusion technique for coping with unwanted thoughts.Virtual Real, 23(2), 179-185. doi: 10.1007/s10055-018-0372-1
[59] Regan, E. C., & Price, K. R. (1994). The frequency of occurrence and severity of side-effects of immersion virtual-reality.Aviat Sp Environ Med, 65(6), 527-530.
[60] Riches S., Jeyarajaguru P., Taylor L., Fialho C., Little J., Ahmed L., … Valmaggia L. (2023). Virtual reality relaxation for people with mental health conditions: A systematic review.Soc Psychiatry Psychiatr Epidemiol, 58(7), 989-1007. doi: 10.1007/s00127-022-02417-5
[61] Riva G., Bacchetta M., Gaggioli A., Anolli L., Galimberti C., Molinari E., … Orsi G. (2001). The VEPSY updated project: Virtual reality in clinical psychology.Cyberpsychology Behav, 4(4), 449-455. doi: 10.1089/109493101750527006
[62] Rodrigues I. M., Lima A. G., Dos Santos A. E., Santos A. C., do Nascimento L. S., Serra M. V., … Zanona, A. de F. (2022). A single session of virtual reality improved tiredness, shortness of breath, anxiety, depression and well-being in hospitalized individuals with COVID-19: A randomized clinical trial.J Pers Med, 12(5), 829. doi: 10.3390/jpm12050829
[63] Rus-Calafell M., Garety P., Sason E., Craig T. J., & Valmaggia L. R. (2018). Virtual reality in the assessment and treatment of psychosis: A systematic review of its utility, acceptability and effectiveness.Psychol Med, 48(3), 362-391. doi: 10.1017/S0033291717001945
[64] Schleider J. L., Mullarkey M. C., & Weisz J. R. (2019). Virtual reality and web-based growth mindset interventions for adolescent depression: Protocol for a three-arm randomized trial.JMIR Res Protoc, 8(7), e13368. doi: 10.2196/13368
[65] Shah L. B., Klainin-Yobas P., Torres S., & Kannusamy P. (2014). Efficacy of psychoeducation and relaxation interventions on stress-related variables in people with mental disorders: A literature review.Arch Psychiatr Nurs, 28(2), 94-101. doi: 10.1016/j.apnu.2013.11.004
[66] Smith, K. (2014). Mental health: A world of depression. Nature, 515(7526), 181. doi: 10.1038/515180a
[67] Souchet A. D., Lourdeaux D., Burkhardt J. M., & Hancock P. A. (2023a). Design guidelines for limiting and eliminating virtual reality-induced symptoms and effects at work: A comprehensive, factor-oriented review.Front Psychol, 14, 1161932 . doi: 10.3389/fpsyg.2023.1161932
[68] Souchet A. D., Lourdeaux D., Pagani A., & Rebenitsch L. (2023b). A narrative review of immersive virtual reality’s ergonomics and risks at the workplace: Cybersickness, visual fatigue, muscular fatigue, acute stress, and mental overload.Virtual Real, 27(1), 19-50. doi: 10.1007/s10055-022-00672-0
[69] Souchet A. D., Philippe S., Lourdeaux D., & Leroy L. (2022). Measuring visual fatigue and cognitive load via eye tracking while learning with virtual reality head-mounted displays: A review.Int J Hum Comput Interact, 38(9), 801-824. doi: 10.1080/10447318.2021.1976509
[70] Stanney K., Lawson B. D., Rokers B., Dennison M., Fidopiastis C., Stoffregen T., … Fulvio J. M. (2020). Identifying causes of and solutions for cybersickness in immersive technology: Reformulation of a research and development agenda.Int J Hum Comput Interact, 36(19), 1783-1803. doi: 10.1080/10447318.2020.1828535
[71] Taher R., Hsu C. W., Hampshire C., Fialho C., Heaysman C., Stahl D., Shergill S., & Yiend J. (2023). The safety of digital mental health interventions: Systematic review and recommendations.JMIR Ment Heal, 10, e47433. doi: 10.2196/47433
[72] The Lancet Psychiatry. (2024). Global burden of disease 2021: Mental health messages.Lancet Psychiatry, 11(8), 573. doi: 10.1016/S2215-0366(24)00222-0
[73] Turan K. S., Yangoz S. T., Ozer Z. (2023). Effectiveness of virtual reality interventions on physiological and psychological outcomes of adults with cardiovascular disease: A systematic review and meta-analysis.J Nurs Scholarship, 55, 949-966. doi: 10.1111/jnu.12885
[74] Vasser, M., & Aru, J. (2020). Guidelines for immersive virtual reality in psychological research.Curr Opin Psychol, 36, 71-76. doi: 10.1016/j.copsyc.2020.04.010
[75] Wiebe A., Kannen K., Selaskowski B., Mehren A., Thoene A. K., Pramme L., … Braun N. (2022). Virtual reality in the diagnostic and therapy for mental disorders: A systematic review. Clin Psychol Rev, 98, 102213. doi: 10.1016/j.cpr.2022.102213
[76] Wong K. P., Lai C. Y., & Qin J. (2023). Systematic review and meta-analysis of randomised controlled trials for evaluating the effectiveness of virtual reality therapy for social anxiety disorder.J Affect Disord, 333, 353-364. doi: 10.1016/j.jad.2023.04.043
[77] Wu Y., Wang N., Zhang H., Sun X., Wang Y., & Zhang Y. (2023). Effectiveness of Virtual Reality in Symptom Management of Cancer Patients: A Systematic Review and Meta-Analysis.J Pain Symptom Manage, 65(5), e467-e482. doi: 10.1016/j.jpainsymman. 2023.01.023
[78] Yen, H. Y., & Chiu, H. L. (2021). Virtual reality exergames for improving older adults’ cognition and depression: A systematic review and meta-analysis of randomized control trials.J Am Med Dir Assoc, 22(5), 995-1002. doi: 10.1016/j.jamda.2021.03.009
[79] Young M. S., Brookhuis K. A., Wickens C. D., & Hancock P. A. (2015). State of science: Mental workload in ergonomics.Ergonomics, 58(1), 1-17. doi: 10.1080/00140139.2014.956151
[80] Zakers, A., & Cimolai, V. (2023). Complementary and integrative medicine and eating disorders in youth: Traditional yoga, virtual reality, light therapy, neurofeedback, acupuncture, energy psychology techniques, art therapies, and spirituality.Child Adolesc Psychiatr Clin N Am, 32(2), 421-450. doi: 10.1016/j.chc.2022.08.014
[81] Zhang Q., Fu Y., Lu Y., Zhang Y., Huang Q., Yang Y., .. Li M. (2021). Impact of virtual reality-based therapies on cognition and mental health of stroke patients: Systematic review and meta-analysis.J Med Internet Res, 23(11), e31007. doi: 10.2196/31007
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